Below are some excerpts from recent studies and where you can Buy Kratom:
Evaluation of Antioxidant and Antibacterial Activities of Mitragyna Speciosa (KRATOM)
The screening of antioxidant and antimicrobial activity performed on M. speciosa leaf extracts which was traditionally used as herbs shows that they are endowed with potentially exploitable free radical scavenging and antimicrobial activity. Hence, M. speciosa leaf could be used as an easy accessible source of natural antioxidants and antimicrobial agent. Further purification of the active compounds and in vivo evaluation of antioxidant and antimicrobial activity along with toxicity studies of the extracts from M. speciosa are therefore suggested for further studies.
Opioids cause respiration problems while natural substances like Kratom do not
In animal studies where rats were given mitragynine, those rats had no respiratory depression. This opens the possibility of someday developing a pain medication as effective as morphine but without the risk of accidentally overdosing and dying.
A team of researchers focusing on the potential mental health benefits of nicotine is now suggesting that this often-misunderstood substance may hold secret, anti-aging properties for the brain. To be clear, scientists have known for decades that nicotine has some very special characteristics.
For example, ask any smoker, and they will confirm. Nicotine suppresses the appetite. If nicotine can trick the brain into thinking that it isn’t hungry, then perhaps it possesses other magical mental capabilities, as well.
This ideology is the basis for a new study from researchers of the Texas A&M College of Medicine. Led by Dr. Ursula Winzer-Serhan, the research team drew considerable criticism after publishing their findings. Many in the academic and medical communities accused the scientists of endorsing and promoting smoking to improve brain functions. However, the truth is far less devious.
Nicotine is a natural-occurring chemical found in such everyday foods as tomatoes, potatoes, and eggplant. And while tobacco cigarettes and cigars happen to contain nicotine as well, most medical experts agree that it’s not the nicotine in cigarettes that causes all the problems. It’s the tar and chemicals in combustible cigarettes that produce carcinogenic smoke.
The Texas A&M team suggests that ingestion of nicotine for its possible health benefits does not necessarily require people to smoke. In fact, they firmly believe the opposite.
Overview of the Texas A&M vaping and nicotine study
The Texas A&M study is entitled, Evaluation of Chronic Oral Nicotine Treatment in Food Consumption, Body Weight and [125I] Epibatidine Binding in Adult Mice. The report and all its findings is available via the Open Access Journal of Toxicology, The underlying theory involves the idea that nicotine may be a potent neuroprotective agent for the brain.
If proven to be true, nicotine consumption may slow the aging process of human brain functions. However, the scientists first wanted to test their theories on non-human test subjects. So, the Texas A&M team selected a group of furry and friendly mice.
The mice were divided into three distinct groups: Low-Nicotine, Medium-Nicotine, and High-Nicotine consumption levels.
Next, the researchers would mix tiny drops of liquid nicotine extract into the mice’s drinking water.
A control group of mice was given only pure, nicotine-free drinking water.
Meanwhile, the mice would be attached to a series of neurotransmitters while the scientists monitored their brain activities.
What the researchers discovered is that the low- and medium-nicotine mice exhibited so significant signs of diminished appetite, weight vacillations, or fluctuations in neuroactivity. However, those mice that received the higher doses of liquid nicotine ate less, gained less weight, and registered increased brain activity.
They also witnessed no substantial increases in anxiety levels for either of the three control groups of mice. In fact, the more nicotine that the mice ingested, the less anxious they became overall. It was this data acquired from the neurotransmitters that leads the researchers to theorize that nicotine may have a more positive effect on the aging process of the brain than the scientific community may currently believe.
Still, the researchers wanted to make perfectly clear that they are definitely not endorsing smoking as a method of ingesting nicotine.
“Even if these weren’t very preliminary results, smoking results in so many health problems that any possible benefit of the nicotine would be more than cancelled out. However, smoking is only one possible route of administration of the drug, and our work shows that we shouldn’t write-off nicotine completely.”
The Texas A&M scientists also suggest that more research in this field of study are warranted before any definitive conclusions can be made. But the results of this first study seem to be very promising, and they plan to continue forward. The next project will involve the testing of nicotine for “potential anti-ageing effects using aged animal models.” Only older mice need apply.
Levels of risky compounds found in e-liquids are no cause for alarm
Prof. Peter Hajek, who is the director at the Tobacco Dependence Research Unit, at Queen Mary University of London (QMUL), said, “All three findings are likely to be presented as generating concerns about vaping, but none provides a cause for alarm.”
He thinks that the highlighted respiratory symptoms are higher in double users, as these tend to be heavy smokers who are struggling to quit, hence tend to use both products. “The most likely explanation is that heavier smokers are more likely to suffer from respiratory symptoms, and are also more likely to try to quit but fail to stop smoking completely. This could lead to heavy smokers with respiratory symptoms ending up in the dual users group,” he said.
“It is the dose that makes the poison. No information is provided on whether these chemicals are inhaled at levels that can cause harm, or how these levels compare with levels inhaled by smokers. Smokers who switch to vaping report significant improvements, e.g. in asthma, which suggests that such a switch reduces respiratory irritation and is beneficial for lung health.”Prof. Peter Hajek, who is the director at the Tobacco Dependence Research Unit, at Queen Mary University of London
In line with what studies measuring dangerous substances in e-liquids have indicated, Hajek thinks that it is the amounts people are exposed to that matter. “It is the dose that makes the poison. No information is provided on whether these chemicals are inhaled at levels that can cause harm, or how these levels compare with levels inhaled by smokers. Smokers who switch to vaping report significant improvements, e.g. in asthma, which suggests that such a switch reduces respiratory irritation and is beneficial for lung health.”
Improved lung function observed in smokers who switch to vaping
On the topic of arterial stiffness caused by nicotine, Hayek pointed out that there are other things that have the same effect on the body, and are considered irrelevant in terms of health risks. “This is a well-known stimulant effect of nicotine that has little relevance for health. Drinking coffee has the same effect, only greater and longer lasting (as does watching a dramatic football match).”
“This is a well-known stimulant effect of nicotine that has little relevance for health. Drinking coffee has the same effect, only greater and longer lasting (as does watching a dramatic football match).”Prof. Peter Hajek, who is the director at the Tobacco Dependence Research Unit, at Queen Mary University of London
A study conducted last year by Prof. Hayek himself and published in the Journal of Addiction Research and Therapy, which focused on a number of smokers who had switched to vaping, found that the greater number of the study participants had experienced a decrease in respiratory infections.
The new study was published in “Regulatory Toxicology and Pharmacology” and showed what exactly is hiding in ecig vapor compared to the contents of cigarette smoke. Scientists ran tests on three flavors ofBlu ecigs and two flavors of SKYCigs. They also tested Marlboro Golds and Lambert & Butler cigarettes. Finally, they tested the ordinary room air as a baseline to use as they compared the results.
The researchers specifically looked for 8 toxins in this study: carbon monoxide, carbonyls, phenolics, volatiles, metals, tobacco-specific nitrosamines, polyaromatic amines, and polyaromatic hydrocarbons. It was no surprise that tobacco cigarette smoke was full of poisonous chemicals. But researchers were shocked to see that the toxins in ecigarette vapor were quite similar to the normal toxins found in regular room air. In fact, there was no major increase in toxins between normal air and ecig vapor.
Instead of deadly toxins, the ecig vapor only contained propylene glycol, water, and small traces of flavoring and nicotine additives. In order to register any degree of toxicity, the scientists had to use 99 puffs of an ecig to get even the tiniest measurement of 0.18 milligrams of HPHC’s. To put that in perspective, a single puff of a Marlboro Gold cigarette measured 30.6 milligrams. In a puff-to-puff comparison, the cigarettes had 2000 times more toxins than the e-cigs.
Within the vaping community, an RDA is known for producing the most pure, and best tasting flavor. “Cloud Chasers” or people wanting to blow the biggest, thickest clouds favor RDAs over anything else. The RDA’s coils are capable of exotic builds, adding extra coils, different size coils, etc.. for the most extreme clouds and flavors. If your wick (cotton) goes bad in an RDA, it is very easy replaceable by the average person. You are able to find the best build for your goal in vaping, whether it be cloud chasing, or trying to get the best flavor.
Cons of a Rebuild-able Drip Atomizer (RDA)
An RDA doesn’t have a tank for holding your e-Liquid, meaning you will have to drip your juice every couple hits. Rebuilding your coils isn’t easy, and may have to have to pay a professional to rebuild them for you. RDA’s tend to be a little more expensive overtime due to the original cost of the product. Also, when trying new builds to find your favorite build of coils, it can get quite expensive if you have a professional do it.
Pros of a Vape Atomizer
An atomizer’s are generally very cheap, and can last for upwards of three weeks. An atomizer is very easy to replace. You will be able to fill a tank of juice, compared to an RDA in which you are constantly dripping juice onto your coils and wick. For a lot of people, it is simply for convenient. Whilst your atomizer wick is good, and not burnt, your flavor will be very good.
Cons of a Vape Atomizer
Have maximums of how high of wattage it will allow you to vape at without burning it. Once your atomizer is primed with one juice, if you decide to use a new juice, it will taint the flavor of your new juice with hints of your old juice. Unfortunately, if you hit your mod at too high of a wattage for your atomizer, it will burn it in just one hit and ruin that atomizer.
Using vapor pens with e liquid has been heralded as the new and improved, safer way to “smoke” when compared to outdated methods like cigarettes or hookah. There are several reasons why someone might choose to go this path less traveled that make perfect, practical sense.
Chemically and Tastily Savvy
Probably the biggest reason someone would choose to use e liquid is because the amount a chemical toxins is significantly less than traditional tobacco. For the overwhelming majority of products, the primary ingredients consist of only glycerin, water, nicotine, propylene glycol, and usually flavor. When compared to the overwhelming list of cancer causing, stomach turning chemicals found in cigarettes, it’s obvious which is the better option. An added bonus of using e liquids is you can pick whatever flavor suits you. The varieties that are available ensure that every person will never get bored with their liquid. No more one note shows.
Aiding Quitting
Many people have dealt with the frustrating process of trying to quit smoking cold turkey. It can make anger, hunger, and anxiety reach a crescendo that makes the process feel not worth while. The liquid allows people to transition from smoking cigarettes into safer methods. Because the liquids contain nicotine, they fulfill the craving for that component without all the other chemical garbage. If people wish to eventually eliminate that ingredient, e liquids are available without nicotine so users can still get the tasty flavor without being dependent on the nicotine.
No Social Stigma
The least amongst the reasons but still worth noting is that using e liquids is not as off putting and smoking cigarettes. Cigarettes are viewed by many as a health faux pas that some may wish not to navigate. E liquids are the new, safe standard for people with “smoking” habits. Users need not be weighed down by the negative consequences that traditional smoking can have.
There are numerous reasons why people choose to vape rather than to smoke. The primary reason is cost. It is far cheaper to buy E liquid and a reusable vape device than it is to buy a carton of cigarettes.
Using a vape pen is cheaper because the e-juice that goes in the pen’s chamber is cheaper to buy. The e-juice also lasts a long time. A 120ML bottle of e-juice can last 10 or more days which is far cheaper than a carton of cigarettes.
The truth is simple. People use vape pens because it gives them more options. This includes being able to enjoy nicotine-free products and being able to enjoy a wider selection of vaping products. Nevertheless, the advantages of vaping go beyond mere cost.
Some people use vape pens because they see them as a better alternative to traditional smoking. They may even choose to vape to help them quit smoking. They start off with a flavored E-liquid at a certain nicotine level. Then they will gradually taper off the nicotine until all they are using is a flavored liquid. Using vaping is the second primary advantage to using a vape pen.
Next, vapor pens produce water vapor instead of smoke. That means there is no smoke to cling to their hair or clothing plus they are tar free. No yellow tobacco stains and the fresher indoor air is just another advantage to using a vaporizer instead of cigarettes. Ex-smokers find their non-smoking friends are more agreeable to vaping compared to the dangers of secondhand smoke.
What Types of Products Go In Vape Pens
The typical products used inside vape pens include:
e-liquids – made with PG, VG, nicotine, and flavoring
waxes – concentrated form of weed, used in states where marijuana is legal
essential oils – large variety of essential oils can be inhaled with a vape pen instead of a room atomizer
dry herbs – tobacco, marijuana and a wide range of natural herbs in states where marijuana is legal
Users do say that essential oils and dry herbs produce the best vapor. That is true for the majority of vape pens unless the pen that is being used is specifically designed to perform best with a particular product. However, regular e-Liquid is the most popular for a variety of reasons.
How to Choose the Best Vape Pen
Vape pen users should make sure that their pen contains a lithium-ion battery. This type of battery lasts the longest and works well in products that are regularly used. A better vaping experience can also be had if the pen is the kind that works well with multiple types of products instead of having to use a specific product for good results. The pen should also be able to be taken apart for easy cleaning.
Is Using a Vape Pen Safe
Although no one fully knows the possible risks associated with vaping, some studies have shown that vaping is a far safer alternative to smoking. That is because vaping products are simply heated instead of being burned to create ash tar and cigarette smoke. Vape products contain items that are already deemed by the FDA as generally safe to use. On the other hand, cigarettes are known to have hundreds of chemicals; some of them are known carcinogens.
In a nutshell, the advantages of vaping are many.
Lower cost
Less dangerous than cigarettes
Less mess
No lingering odors and stains
No danger of second-hand smoke
Wide assortment of products can be vaped
Discreet and stylish in public
Many people ask us, can vaping can help me to quit smoking? This is a logical question to ask since there is so much research regarding the harmful effects of tobacco.
Let’s first look at some facts.
According to the Centers for Disease Control cigarette smoking causes over 480,000 premature deaths every year in the United States alone. That works out to be almost one in five deaths being contributed to tobacco use.
In fact, smoking tobacco causes more deaths every year than all of these combined: • Human immunodeficiency virus (HIV) • Illegal drug use • Alcohol use • Motor vehicle injuries • Firearm-related incidents
Here are some more interesting facts about tobacco use. More people have died from tobacco use then have died in all wars combined throughout the history of the United States. To put that in perspective roughly 2% of the American population lost their lives during the Civil War alone.
For a full report on all of the harmful effects of tobacco use you can visit the CDC website to learn more.
It’s easy to see why smokers want to know if vaping can help them to quit smoking. One major study says yes vaping can help you to quit smoking. Not only that, but the evidence also concludes that vaping is around 95% safer than tobacco.
This is no small study and nothing to sneeze at. It was done by the Public Health Department in England. The authors and researchers who contributed to the study are well known and highly credible.
The study is titled: E-Cigarettes: An Evidence Update
A report commissioned by Public Health England
Authors: McNeill A, Brose LS, Calder R, Hitchman SC
Institute of Psychiatry, Psychology & Neuroscience, National Addiction Centre, King’s College London UK Centre for Tobacco & Alcohol Studies
Hajek P, McRobbie H (Chapters 9 and 10)
Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry Queen Mary, University of London
UK Centre for Tobacco & Alcohol Studies
1. People who have tried to quit smoking using various methods but have failed could be positively encouraged to try vaping along with behavioral support. 2. Encouraging smokers to switch to vaping could greatly reduce smoking-related deaths and disease. 3. Electronic cigarettes are attracting very few people who have never smoked in the past. 4. On the other hand, this study supports the Cochrane Review findings that vaping can help quit or sharply reduce tobacco consumption. 5. When used as intended, vaping poses no risk of nicotine poisoning. However, E liquid should be packaged in childproof bottles with accurate nicotine content labeling. 6. E cigarettes are around 95% safer than using tobacco. 7. Ongoing research in the use of tobacco versus E liquid is needed.
Two recent worldwide headlines claim that vaping is dangerous. However, their findings are based on misinterpreted research. This ongoing negative media is one explanation for the public’s change in perception about the vaping industry and safety.
Vaping may not be 100% safe but one thing is certain. None of the harmful chemicals involved in smoking-related disease are present in E juice. Furthermore, E juice would have to be heated to an unpalatable level in order to cause the dangerous levels of chemicals like formaldehyde or aldehides as claimed in the main stream media.
Clearly there is a disinformation war being waged on the vaping industry. Fortunately we have studies like the one above that disproves many of the negative claims made by the media. Nevertheless vaping is not without its risks. I suppose nothing in life is.
Using vaping to quit smoking comes down to a choice. It is the lesser of two evils. On the one hand we have a mountain of evidence and data revealing the harmful effects of tobacco. On the other hand we have substances in E liquid that are already approved by the FDA for the use in food and cosmetics.
That does not make the additives used in E juice a 100% safe alternative but it does make it a safer alternative compared to the harmful substances in tobacco.
So what are the possible side effects to vaping?
This is also a reasonable question to ask. E liquid usually contains only four basic ingredients. Nicotine, propylene glycol, water, and food grade flavoring. Vegetable glycerin is also used in combination with propylene glycol.
Let’s look at each ingredient.
Nicotine is an addictive substance however, health researchers are not 100% sure that there’s any health danger beyond that according to one study published in scientific American
The next ingredient is water. Most high-end vape companies manufacture their E liquid using clean healthy water. That is why it’s important to buy your vape juice from a reputable company. They will have a certified lab and only buy top food-grade ingredients.
Propylene glycol is another primary ingredient in E liquid that the FDA has classified as: generally recognized as safe. It can be found in everything from cosmetics to medications and does not seem to be a danger when inhaled. Studies on this date back to the 1940s and can be read about in the Journal of Pharmacology And Experimental Therapeutics, 1947, 91 (1) page 52 to 76
Vegetable glycerin is another primary ingredient in E juice. Unlike propylene glycol, which has been frequently used in breathing treatments, there is little application data on vegetable glycerin. However, we do know that it is a relatively safe substance. It is made from plant oils and can also be found in cosmetic products and herbal remedies.
The final ingredient is flavoring. Since flavoring is a broad term most people assume flavorings are tested for safety regarding inhalation. This does open the doors for concern. Some food ingredients like flower can cause asthma or chronic bronchitis in some people.
Using high grade food flavorings are another reason why you want to buy your E liquid only from a reputable company. They will use only food grade flavorings, ones that are testes as safe and made only by major food manufacturers.
On the other hand a fly-by-night company might use low-quality flavorings that are not FDA approved. These could be of concern to those prone to allergies. It must also be mentioned that flavorings are typically less than 2% of the total content. Compare that to cigarettes that can contain 8.5% or more chemical flavoring.
There is a fifth ingredient called diacetyl which is seldom used but may have some cause for concern. This substance is generally recognized as safe. However, factory workers began to experience health problems in response to being exposed to heavy concentrations every day.
As you can see, electronic cigarettes have four or five basic ingredients that are generally deemed as safe. Vaping health risks seem far lower when we compare them to tobacco, which has hundreds of harmful chemicals — including known carcinogens.
It is no wonder that the UK study has deemed E juice to be 95% safer than cigarette smoking. Another benefit to E liquid is that you can order it without nicotine. This is just another reason why folks are replacing harmful cigarettes with vaping.
So now you have some facts to consider when deciding if vaping can help you to quit smoking. In our minds electronic cigarettes are far safer when compared to the health risks of tobacco.
So yes, vaping can help many folks to quit smoking.
1. The ingredients are safer than tobacco by comparison 2. You can order it with or without nicotine 3. You can find your favorite flavors 4. It is far cheaper than tobacco 5. Major study says it is 95% safer that tobacco
The truth is nothing in life is 100% safe. Sometimes our choices boil down to which is the safest alternative. Tobacco has demonstrated to be a health risk whereas E juice contains ingredients that are already deemed to be generally safe to use. And, your smoking to vaping side effects are far less with vaping. Ultimately the choice is yours and yours alone. Armed with some facts you can now make the best decision when asking: Can vaping help me to quit smoking?
Simply put, vapor’s fatigue is when a person is no longer able to taste the full flavor of an E-liquid as they vape. That is not a chronic problem for the vast majority of people. However, some folks will experience olfactory fatigue.
Vapor’s fatigue, or olfactory fatigue is not unique to those that use e-cigarettes. It’s a well-established fact that cigarette smoking dulls the sense of smell as well as the sense of taste. Even some foods can numb our senses to the flavor if we eat them too often.
Certain dental and medical procedures, as well as medication and drugs, can dull our senses too. The good news is that vapors tongue can be easily mitigated or remedied whereas certain dental or medical procedures will sometimes leave permanent damage to the olfactory nerves.
Most people know that the tongue has an extraordinary ability to sense five distinct flavors. Those are sweet, salty, bitter, sour, and savory. Now, some people may describe these five flavors differently, but according to various journals, these are the top five flavors that we humans recognize.
For instance, most people can recognize fruit as being sweet. They can recognize green apples as sour while most people will recognize bacon as salty. The point is that most people recognize flavors when they taste them.
It is the olfactory sensors within our nasal passage that allow us to recognize different flavors. However, when vapor’s fatigue develops, it sometimes dulls the olfactory sensors causing the flavor of the E-juice to diminish. That is undesirable since many folks use flavored E-liquid because they enjoy the taste.
On the bright side, many ex-smokers say that their sense of taste improves when they make the switch from cigarettes to E-liquid. They also claim their sense of smell is improved and as we all know there are many health benefits to quitting tobacco smoking. With that said how can we overcome vapors fatigue?
The answer to vapor’s fatigue is simple. Drink more water.
The nasal passage is a mucous membrane. The majority of mucus is made up of water. When we are dehydrated our nasal passages become dry, and the mucus becomes thick. That contributes to olfactory fatigue. Therefore, be sure to drink at least eight glasses of clean, healthy water every day. It will go a long way toward relieving olfactory adaptation.
Another way to relieve vapor tongue is to use a room humidifier That is what Ray Marsili recommends in the book titled: Techniques for Analyzing FOOD AROMA (Dean Foods Company, Rockford, Illinois).
Dehydration can also cause a whole host of other problems too. Energy loss, constipation, digestive disorders, urinary tract infection and a whole host of other issues can stem from dehydration. Consequently, it only makes sense to stay hydrated.
Olfactory Fatigue Experiment
At the CMS science fair Julia Sorensen showed how long it takes for olfactory fatigue to set in when she exposed test subjects to various spices. Almond extract, vanilla extract, and cinnamon were just a few of the items she used. She also used a stopwatch and had her test subjects drink water.
Almond extract took the longest to weaken people’s sense of smell. At the other end of her test, in just 13.1seconds the test subjects had diminished smell of cinnamon.It was not conclusive if olfactory fatigue affects males or females more.
If you can no longer taste your favorite E-liquid as strongly as you once did, then simply switch to another flavor for a while. Using this technique is not unlike anything else we humans do. If we eat the same thing often enough, we get tired of it. Mc Donald’s doesn’t taste as good if we eat it every day for a month. But if we don’t eat Mc Donald’s for a month or two it will taste good to us again. So, switching E-Liquid flavors for a while may help you to enjoy your favorite E-liquid again.
In most cases, vapor’s fatigue or vapors tongue is a temporary issue that clears up on its own or one that can be easily remedied using the suggestions above. Drink lots of water, use a room humidifier, or switch flavors for a while. These will often fix the problem.
The vapor’s fatigue methods above are not intended to be medical advice. If your vapor’s fatigue lasts longer than a week, it is best to seek professional medical attention. The problem may go beyond simple olfactory fatigue or vapor’s fatigue.
We hope these suggestions help you to alleviate your vapor’s fatigue or vapors tongue and allow you buy and enjoy your favorite e-juice flavor again! If you want to try a new flavor to reduce your vapor’s fatigue stop buy and see us! We enjoy meeting new people!